EMI Summary: During cytokinesis, a contractile ring consisting of unbranched filamentous actin (F-actin) and myosin II constricts at the cell equator.Unbranched F-actin is generated by formin, and without formin no cleavage furrow forms.In Caenorhabditis elegans, depletion of septin restores furrow ingression in formin mutants.How the cleavage furr
The Method of Reversible Circuits Design with One-gate Prediction
This paper presents an original method of designing reversible circuits.This method is destined to most popular gate set with three types of gates CNT (Control, EMI NOT and Toffoli).The presented algorithm based on graphical representation of the reversible function is called s-maps.This algorithm allows to find optimal or quasi-optimal reversible
HDAC Family Members Intertwined in the Regulation of Autophagy: A Druggable Vulnerability in Aggressive Tumor Entities
The exploitation of autophagy by some cancer entities to support survival and dodge death has been well-described.Though its role as a constitutive hand mask process is important in normal, healthy cells, in the milieu of malignantly transformed and highly proliferative cells, autophagy is critical for escaping metabolic and genetic stressors.In re
Cancer Burden in Latin America and the Caribbean
Background: In Latin America and the Caribbean, the epidemiological transition has been occurring in an unequal Tops manner.Infectious-contagious diseases share space with the increase of chronic nontransmissible diseases, such as cancer, which already represents the second most common cause of death, after cardiovascular illnesses.Objectives: This